Tetrahydrocurcuminoids for Nutritional Supplements
  • Antioxidant action

  • Anti-inflammatory action

  • Chemopreventive properties
PROPOSED MECHANISMS OF ANTIOXIDANT ACTION OF TETRAHYDROCURCUMINOIDS

Free radicals are implicated as mediators in the progression of several chronic diseases and in the deteriorative changes associated with aging.

Tetrahydrocurcuminoids counteract free radicals in 2 ways

  • PREVENTION of free radical formation.

  • INTERVENTION whereby already preformed radicals are quenched.

Tetrahydrocurcuminoids are therefore classified as BIOPROTECTANT.

A set of studies performed by Sabinsa Corporation revealed that the Curcuminoids and Tetrahydrocurcuminoids are more potent antioxidants than the commonly used synthetic antioxidant, Butylated Hydroxytoluene (BHT).

ESTIMATION OF ANTIOXIDANT POTENTIAL

  • In the DPPH radical scavenging method, the ability of an antioxidant to bind the 1:1 diphenyl-2-picrylhydrazyl-radical (a very stable free radical species) is measured, using various concentrations of the selected antioxidants.
  • A compound with high antioxidant potential effectively traps this radical thereby preventing its propagation and the resultant chain reaction.
Click Image for Larger View
         Sabinsa Corporation 2000